Enlisting Synbio for Molecular Communication

Divergent approaches to process information: •Electronics use electrons •Biology uses ions & molecules

Gregory Payne and William Bentley

Divergent approaches to process information:
•Electronics use electrons
•Biology uses ions & molecules

We are developing enabling technologies that employ redox as a modality to span bio-device communication.

Create materials and enlist mechanisms for redox-based signaling:
•Biofabricate multi-functional thin films from stimuli-responsive self-assembling polysaccharides
•Dual film system is electrofabricated with bio-signal transducer film and redox-capacitor film
•Enlist synthetic biology to recognize and transduce molecular information into redox-active intermediate
•Synbio construct recognizes signaling molecule and transduces to a redox intermediate (PAP)
•Detect redox active intermediate as an amplified electrical signal
•Redox-capacitor engages PAP in a redox-cycling mechanism that amplifies electrical output

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Any opinions, findings, and conclusions or recommendations expressed on this website are those of the participants and do not necessarily reflect the views of the National Science Foundation or the participating institutions. This site is maintained collaboratively by principal investigators with Designing Materials to Revolutionize and Engineer our Future awards, independent of the NSF.

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